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Onfim I, Camacho RJ, Vandamme AM, Lemey P: Phylodynamics of the HIV-1 CRF02_AG clade in Cameroon. Infect Genet Evol 2012, 12:453?60. 20. Zhang M, Foley B, Schultz AK, Macke JP, Bulla I, Stanke M, Morgenstern B, Korber B, Leitner T: The role of recombination in the emergence of a complex and dynamic HIV epidemic. Retrovirology 2010, 7:25. 21. Carr JK, Salminen MO, Albert J, Sanders-Buell E, Gotte D
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Ion of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell linesHongwei Zhou1, Amy Imrich1 and Lester Kobzik*1,Address: 1Department of Environmental Health, Harvard School of Public Health, Boston, MA, 02115, USA and 2Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA Email: Hongwei Zhou - hzhou@hsph.harvard.edu; Amy Imrich -
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Eshly isolated AMs from MS-/- mice, the cell lines exhibit decreased phagocytosis of unopsonized titanium dioxide (TiO2), fluorescent latex beads and bacteria (Staphylococcus aureus) compared with the primary AMs from wild type (WT) C57BL/6 mice. Conclusion: Our results indicated that three contiguous murine alveolar macrophage cell lines with MS-/- (ZK1, ZK2 and ZK6) were established successfully
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Tential impact of HIV-1 diversity on both vaccine development and the sustainability of antiretroviral therapies, it is particularly important that molecular epidemiological surveillance is continued in HIV diversity hotspots such as Cameroon. In this study we have focused on characterizing the diversity of gag and nef genes of Cameroonian HIV-1 isolates. These genes are?2013 Tongo et al.; license
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Tion and analysis, decision to publish or preparation of the manuscript.Tongo et al. Virology Journal 2013, 10:29 http://www.virologyj.com/content/10/1/Page 7 of17. Montavon C, Vergne L, Bourgeois A, Mpoudi-Ngole E, Malonga-Mouellet G, Butel C, Toure-Kane C, Delaporte E, Peeters M: Identification of a new circulating recombinant form of HIV type 1, CRF11-cpx, involving subtypes A, G, J, and CRF01-
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Type 1: subtype G is a circulating recombinant form. J Virol 2007, 81:8543?551.doi:10.1186/1743-422X-10-29 Cite this article as: Tongo et al.: Characterization of HIV-1 gag and nef in Cameroon: further evidence of extreme diversity at the origin of the HIV-1 group M epidemic. Virology Journal 2013 10:29.Submit your next manuscript to BioMed Central and take full advantage of:?Convenient online sub
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Type 1: subtype G is a circulating recombinant form. J Virol 2007, 81:8543?551.doi:10.1186/1743-422X-10-29 Cite this article as: Tongo et al.: Characterization of HIV-1 gag and nef in Cameroon: further evidence of extreme diversity at the origin of the HIV-1 group M epidemic. Virology Journal 2013 10:29.Submit your next manuscript to BioMed Central and take full advantage of:?Convenient online sub
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Les 1, 2). The sequences clustered with different clades and circulating recombinant forms distributed throughout the phylogenetic trees (Table 2), consistent with the breadth of HIV-1 diversity previously described in Cameroon. CRF02_AG-like viruses dominated the clade distribution, infecting 50 of the 46 participants for which both genes were sequenced (Figure 2). Participants infected with vir