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Nonevent. All cases with missing information were included in proportional hazard ratio calculations after performing a sensitivity analysis which showed negligible effects of excluding missing data.ImmunohistochemistryImmunohistochemical staining for CNKSR1 (mouse monoclonal antibody CNKSR1 (clone 46), Santa Cruz Biotechnology, TX, USA, #sc-135,870; dilution 1:200) was performed on a Leica BOND-M
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D. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.AbstractBackground: Alveolar macrophages (AM) avidly bind and ingest unopsonized inhaled particles and bacteria through class
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A showed only low sequence similarity to mouse proteins (BLASTP E-Yadetie et al. BMC Genomics 2012, 13:55 http://www.biomedcentral.com/1471-2164/13/Page 6 ofTable 1 Comparison of numbers of selected defensome genes in genomes of Oikopleura and other organismsGene AhR signaling CYP1 genes AhR AhRR ARNT Nuclear receptors NR1I (SXR/CAR/ VDR) NR1H (LXR/FXR) NR1C (PPAR) Nrf2-signaling Nrf2 Keap1 MafKaO
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A showed only low sequence similarity to mouse proteins (BLASTP E-Yadetie et al. BMC Genomics 2012, 13:55 http://www.biomedcentral.com/1471-2164/13/Page 6 ofTable 1 Comparison of numbers of selected defensome genes in genomes of Oikopleura and other organismsGene AhR signaling CYP1 genes AhR AhRR ARNT Nuclear receptors NR1I (SXR/CAR/ VDR) NR1H (LXR/FXR) NR1C (PPAR) Nrf2-signaling Nrf2 Keap1 MafKaO
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R of proteins either indirectly or directly connected to MAPK/ERK signaling (Ras, ERBB2, Myc) [4, 31]. A limitation of this study was that the dataset did not include all clinical variables, such as complete TNM staging and chemotherapy treatment, and thus we could not evaluate all variables that might impact survival. While the HRs of known clinical (TNM system N and M stage) and pathological var
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Ribution of CNKSR1 and nuclear p-ERK expression levels, possibly indicating regulation of MAPK pathway signaling less connected to absolute CNKSR1 expression levels. In addition, the SEER TMA studied has been used in multiple previous biomarker studies, several of which have been validated in additional larger cohorts [4, 22]. CNKSR1 may represent an additional prognostic marker in pancreatic canc
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Tion and analysis, decision to publish or preparation of the manuscript.Tongo et al. Virology Journal 2013, 10:29 http://www.virologyj.com/content/10/1/Page 7 of17. Montavon C, Vergne L, Bourgeois A, Mpoudi-Ngole E, Malonga-Mouellet G, Butel C, Toure-Kane C, Delaporte E, Peeters M: Identification of a new circulating recombinant form of HIV type 1, CRF11-cpx, involving subtypes A, G, J, and CRF01-
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Tion and analysis, decision to publish or preparation of the manuscript.Tongo et al. Virology Journal 2013, 10:29 http://www.virologyj.com/content/10/1/Page 7 of17. Montavon C, Vergne L, Bourgeois A, Mpoudi-Ngole E, Malonga-Mouellet G, Butel C, Toure-Kane C, Delaporte E, Peeters M: Identification of a new circulating recombinant form of HIV type 1, CRF11-cpx, involving subtypes A, G, J, and CRF01-